Le Fort Fracture: Causes, Symptoms & Treatment

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Le Fort fractures, classified by René Le Fort based on his experiments at the University of Lille, represent a complex set of facial bone injuries that involve separation of all or a portion of the midface from the cranial base. These fractures, often resulting from significant blunt force trauma such as motor vehicle accidents, typically manifest with noticeable symptoms including facial swelling, malocclusion, and potential cerebrospinal fluid rhinorrhea, requiring careful diagnosis and management by maxillofacial surgeons to ensure proper functional and aesthetic outcomes. Computed tomography (CT) scans play a crucial role in accurately assessing the extent and severity of a le fort fracture, guiding the subsequent surgical planning and reconstruction.

Le Fort fracture anatomy

Image taken from the YouTube channel Sam Webster , from the video titled Le Fort fracture anatomy .

Le Fort fractures represent a distinct and clinically significant category of midface fractures. These injuries are critical to understand in the broader context of facial trauma management. Characterized by specific patterns of maxillary and adjacent bone fractures, they can result in substantial functional and aesthetic impairments.

Clinical Significance in Facial Trauma

The clinical importance of Le Fort fractures stems from their potential to compromise essential functions. These include breathing, eating, speech, and vision. Effective management requires a thorough understanding of the fracture patterns, associated injuries, and appropriate treatment strategies.

Early recognition and intervention are crucial. This helps minimize long-term complications and optimize patient outcomes. The severity and complexity of these fractures often necessitate a multidisciplinary approach, involving specialists from otolaryngology, oral and maxillofacial surgery, ophthalmology, and neurosurgery.

A Historical Perspective: René Le Fort's Contribution

The classification system used to categorize these fractures is named after René Le Fort, a French surgeon. His groundbreaking work in the late 19th and early 20th centuries laid the foundation for our modern understanding of midface fracture patterns.

Le Fort conducted experiments on cadaveric heads. He systematically applied blunt force trauma to identify predictable fracture lines. His meticulous observations led to the classification of fractures into three main types: Le Fort I, Le Fort II, and Le Fort III. These categories define the level and extent of maxillary detachment from the skull base.

Le Fort's legacy continues to influence the diagnosis and treatment of these complex injuries. His classification system provides a standardized framework for communication and treatment planning among surgeons.

Common Causes of Le Fort Fractures

Le Fort fractures typically result from high-energy impacts to the midface. Common causes include:

  • Motor Vehicle Accidents: These are a leading cause due to the forces generated during collisions.

  • Falls: Particularly in the elderly, falls can result in significant facial trauma.

  • Assault: Blunt force trauma from interpersonal violence can also lead to Le Fort fractures.

  • Other Trauma: Sporting injuries, industrial accidents, and other forms of blunt trauma can also be implicated.

Understanding the mechanisms of injury is essential. It helps to anticipate the potential fracture patterns and associated injuries. This knowledge also guides the diagnostic and treatment approach. High-velocity impacts often result in more complex and comminuted fractures. These require more extensive surgical reconstruction.

Anatomy and Le Fort Classification: The Foundation for Understanding

Le Fort fractures represent a distinct and clinically significant category of midface fractures. These injuries are critical to understand in the broader context of facial trauma management. Characterized by specific patterns of maxillary and adjacent bone fractures, they can result in substantial functional and aesthetic impairments. Clinical Significance hinges on a thorough comprehension of facial anatomy and the Le Fort classification system, providing the framework for accurate diagnosis and effective treatment planning.

Relevant Anatomical Structures in Le Fort Fractures

A clear understanding of midface anatomy is paramount in appreciating the nature and extent of Le Fort fractures. Several key structures play a vital role in defining the fracture patterns and associated clinical manifestations.

The Maxilla: Central to Le Fort Fracture Patterns

The maxilla, or upper jaw bone, is central to all Le Fort fracture types. In a Le Fort I fracture, the maxilla is horizontally separated from the rest of the face above the level of the teeth and hard palate. This often results in a floating palate.

In Le Fort II fractures, the maxilla, along with the nasal bones and medial orbital rim, forms a pyramidal segment that is separated from the rest of the skull base. This involves the infraorbital rim.

Le Fort III fractures involve complete craniofacial disjunction, where the entire midface is separated from the cranial base. The maxilla, zygomas, nasal bones, and orbits all become a single floating segment.

The Zygomatic Bone (Cheekbone): Contributing to Facial Width and Structure

The zygomatic bone, commonly known as the cheekbone, is critical for facial width and projection. While not directly involved in Le Fort I fractures, the zygoma plays a crucial role in Le Fort II and III injuries.

In these fracture types, the zygomatic arch and the zygomaticofrontal suture are frequently involved, impacting facial aesthetics and potentially disrupting the orbital floor. This can lead to enophthalmos (sunken eye) or diplopia (double vision).

The Nasal Bone: A Frequent Site of Injury

Due to its prominent position and relatively weak structure, the nasal bone is often fractured in conjunction with Le Fort injuries. Particularly in Le Fort II and III fractures, the nasal bones are almost always involved.

This can lead to nasal deformities, airway obstruction, and anosmia (loss of smell). Assessment and management of nasal injuries are essential components of treating Le Fort fractures.

The Orbital Bones (Eye Socket): Protecting the Globe and Enabling Vision

The orbital bones, which form the eye socket, are vulnerable in Le Fort fractures, especially the orbital floor and medial orbital wall. Fractures in these areas can lead to serious complications.

These complications include enophthalmos, diplopia, and entrapment of the inferior rectus muscle. Careful evaluation and surgical repair of orbital fractures are crucial to prevent long-term visual impairment.

The Pterygoid Plates: Defining the Posterior Extent of Fractures

The pterygoid plates, located on the sphenoid bone, are significant in defining the posterior extent of Le Fort fractures. These plates articulate with the maxilla and contribute to the stability of the midface.

The degree of pterygoid plate involvement helps differentiate between the different Le Fort classifications and influences the surgical approach required for repair. Complete separation of the pterygoid plates is often observed in Le Fort III fractures.

Le Fort Classification System: A Structured Approach to Midface Fractures

The Le Fort classification system, developed by French surgeon René Le Fort, provides a standardized method for categorizing midface fractures based on their anatomical location and extent. Understanding this system is essential for accurate diagnosis, treatment planning, and communication among healthcare professionals.

Le Fort I: The Horizontal Fracture

A Le Fort I fracture, also known as a Guérin fracture, is a horizontal fracture that separates the maxillary alveolus (the part of the maxilla that holds the teeth) and palate from the rest of the midface.

The fracture line typically runs above the apices of the teeth, through the nasal septum, and across the inferior aspect of the pterygoid plates. Clinically, this fracture results in mobility of the palate and upper teeth as a single unit.

Le Fort II: The Pyramidal Fracture

The Le Fort II fracture is a pyramidal fracture that involves the maxilla, nasal bones, and medial aspects of the orbital floor. The fracture line extends from the nasal bridge, through the medial orbital wall and infraorbital rim, down through the anterior maxilla, and posteriorly to the pterygoid plates.

This results in a free-floating segment that includes the nose and the entire upper jaw. Patients with Le Fort II fractures often present with periorbital edema, subconjunctival hemorrhage, and step-off deformities along the infraorbital rim.

Le Fort III: Complete Craniofacial Disjunction

A Le Fort III fracture represents complete craniofacial disjunction. This severe injury separates the entire midface from the cranial base. The fracture line extends through the nasal frontal suture, along the medial orbital wall, through the floor of the orbit, through the lateral orbital wall at the zygomaticofrontal suture, and posteriorly through the pterygoid plates.

This results in the entire midface (including the maxilla, zygomas, nasal bones, and orbits) becoming a single, mobile segment. Patients with Le Fort III fractures often exhibit significant facial edema, flattening of the midface, and potential cerebrospinal fluid (CSF) leaks.

Diagnosis: Identifying Le Fort Fractures - From Initial Assessment to Imaging

[Anatomy and Le Fort Classification: The Foundation for Understanding Le Fort fractures represent a distinct and clinically significant category of midface fractures. These injuries are critical to understand in the broader context of facial trauma management. Characterized by specific patterns of maxillary and adjacent bone fractures, they can result...] Accurate and timely diagnosis is crucial in the management of Le Fort fractures. The diagnostic process involves a multifaceted approach, beginning with the initial assessment in the emergency room and culminating in detailed radiological evaluation. Each step provides valuable information that guides treatment planning and ultimately impacts patient outcomes.

Initial Management in the Emergency Room

The immediate care of a patient suspected of having a Le Fort fracture in the emergency room follows established trauma protocols. The focus is on stabilizing the patient and preventing further injury. This involves a rapid and systematic evaluation, adhering to the principles of Advanced Trauma Life Support (ATLS).

Primary Survey: Airway, Breathing, Circulation

The primary survey is the cornerstone of initial management. Prioritizing airway patency is paramount, as facial fractures can compromise the upper airway due to swelling, bleeding, or dislodged bony fragments. Endotracheal intubation may be necessary to secure the airway. Breathing is assessed to ensure adequate ventilation and oxygenation, addressing any associated chest injuries. Circulatory status is evaluated to identify and manage any signs of hypovolemic shock secondary to blood loss.

Hemorrhage Control

Facial injuries are often associated with significant bleeding. Direct pressure is the initial step in controlling hemorrhage. Anterior and posterior nasal packing may be required to manage epistaxis. In some cases, surgical exploration and ligation of bleeding vessels may be necessary. Early and effective hemorrhage control is vital to preventing further complications and maintaining hemodynamic stability.

Thorough Clinical Examination

Following the initial stabilization, a comprehensive clinical examination is performed to assess the extent of the injury. This involves a detailed evaluation of the facial region, including soft tissues and bony structures.

Assessment of Edema and Ecchymosis

Edema (swelling) and ecchymosis (bruising) are common findings in Le Fort fractures. The distribution and severity of these signs can provide clues to the location and extent of the fracture. Periorbital ecchymosis, often referred to as "raccoon eyes," suggests a fracture involving the orbital region.

Evaluation for Malocclusion and Open Bite Deformities

Malocclusion, or misalignment of the teeth, is a frequent finding in Le Fort fractures. Palpation of the maxilla may reveal mobility and crepitus. An open bite deformity, where the anterior teeth do not meet when the posterior teeth are occluded, is suggestive of a Le Fort I or II fracture.

Neurological Assessment

A thorough neurological assessment, including cranial nerve examination, is essential to rule out associated neurological injuries. Special attention should be paid to the trigeminal nerve (V), which provides sensation to the face, and the facial nerve (VII), which controls facial expressions. Damage to these nerves can result in numbness, paresthesia, or facial paralysis.

Radiological Evaluation

Radiological imaging is indispensable for confirming the diagnosis of Le Fort fractures and delineating the fracture patterns. While various imaging modalities are available, computed tomography (CT) is considered the gold standard.

CT Scan: The Gold Standard

Computed tomography (CT) scanning provides detailed cross-sectional images of the facial skeleton, allowing for precise identification of fracture lines and displacement. Axial, coronal, and sagittal reconstructions can be generated to visualize the fractures in three dimensions. CT imaging is particularly useful for assessing the involvement of the orbits, nasal cavity, and skull base.

X-ray: Role in Initial Screening

While CT scanning is the preferred imaging modality, plain x-rays may be used as an initial screening tool in certain situations. Waters' view, a specific radiographic projection, can be helpful in visualizing the maxillary sinuses and orbital floors. However, x-rays have limited sensitivity and specificity compared to CT scans.

Radiologist Interpretation

The interpretation of radiological images requires the expertise of a qualified radiologist. The radiologist carefully analyzes the images to identify fracture lines, assess the degree of displacement, and evaluate for associated soft tissue injuries. The radiologist's report provides valuable information to the surgical team, guiding treatment planning and surgical intervention.

Treatment Planning and Surgical Intervention: Restoring Facial Structure and Function

Following accurate diagnosis and classification, the focus shifts to treatment planning and surgical intervention. The overriding goal is to restore the patient's facial structure, achieving functional occlusion and an acceptable aesthetic outcome. This intricate process requires meticulous planning and skilled execution.

The Multidisciplinary Approach

Successfully managing Le Fort fractures necessitates a collaborative approach, involving oral and maxillofacial surgeons, plastic surgeons, otolaryngologists, and ophthalmologists. Each specialist contributes their unique expertise to address the multifaceted nature of these injuries. Clear communication and coordinated surgical planning are paramount for optimal patient outcomes.

Pre-Operative Considerations: Preparing for Surgery

Careful pre-operative assessment is vital. This involves identifying and addressing any concomitant injuries, such as intracranial trauma or cervical spine injuries, which may necessitate a staged surgical approach.

Optimizing the patient's medical condition is equally important. Pre-existing medical conditions like diabetes or cardiovascular disease must be carefully managed to minimize surgical risks and promote healing. A thorough review of the patient's medications and allergies is also crucial.

Surgical Techniques: Rebuilding the Midface

The primary surgical technique for repairing Le Fort fractures is Open Reduction and Internal Fixation (ORIF). This involves surgically exposing the fracture sites, carefully reducing the fractures to their anatomical position, and stabilizing them with plates and screws.

Open Reduction and Internal Fixation (ORIF) Step-by-Step

The ORIF procedure typically involves a systematic approach:

  1. Exposure of Fracture Sites: Incisions are strategically placed to access the fractured bones, minimizing visible scarring. Common approaches include intraoral incisions and coronal incisions.

  2. Reduction of Fractures: The fractured segments are carefully manipulated and repositioned to their original anatomical alignment. This often requires specialized instruments and techniques to ensure accurate reduction.

  3. Fixation: Small titanium plates and screws are used to rigidly fixate the reduced fracture segments. Titanium is biocompatible and provides excellent stability, promoting bone healing. The choice of plate and screw size depends on the fracture pattern and bone quality.

Intermaxillary Fixation (IMF) and Arch Bars

In some cases, Intermaxillary Fixation (IMF) is used as an adjunct to ORIF. IMF involves temporarily immobilizing the maxilla and mandible using arch bars and wires. This helps to establish proper occlusion during the healing process. Once the fractures have healed sufficiently, the IMF is released.

The Operating Room: Setting the Stage for Success

The operating room setup for Le Fort fracture repair requires specialized equipment and instruments. This includes a surgical microscope, power saws, drills, plates, screws, and instruments for manipulating and reducing fractures. The room should be organized to allow for efficient workflow and access to all necessary equipment.

Anesthesia Considerations: The Role of the Anesthesiologist

Anesthesia plays a critical role in Le Fort fracture repair. General anesthesia is typically required to provide adequate muscle relaxation and pain control. The anesthesiologist must carefully monitor the patient's vital signs and manage potential complications, such as airway obstruction or bleeding. Close communication between the surgeon and anesthesiologist is essential for a safe and successful surgical outcome.

Post-Operative Management and Potential Complications: Ensuring Optimal Recovery

Following accurate diagnosis and classification, the focus shifts to treatment planning and surgical intervention. The overriding goal is to restore the patient's facial structure, achieving functional occlusion and an acceptable aesthetic outcome. This intricate reconstructive phase, however, is only one part of the recovery journey. Comprehensive post-operative management is just as critical to ensure optimal healing and minimize the risk of complications that could jeopardize the surgical result. This section outlines essential aspects of post-operative care and highlights the potential pitfalls that warrant careful attention.

Immediate Post-Operative Care: Vigilance in the Initial Phase

The immediate post-operative period demands close monitoring and proactive intervention. Patients may require admission to the intensive care unit (ICU), particularly those with significant trauma or pre-existing medical conditions. The primary aims during this phase are to stabilize the patient and address any immediate threats to their well-being.

ICU Monitoring and Stabilization

ICU monitoring provides continuous assessment of vital signs, neurological status, and respiratory function. Patients with Le Fort fractures often experience significant swelling, which can compromise airway patency. In such cases, endotracheal intubation or tracheostomy may be necessary.

Pain Management and Antiemetic Control

Effective pain management is paramount to patient comfort and promotes early mobilization. Opioid analgesics are frequently used in the immediate post-operative period, but their use should be carefully titrated to minimize the risk of respiratory depression. Adjunctive pain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen, can also be beneficial. Nausea and vomiting are common side effects of anesthesia and opioid analgesics. Prophylactic antiemetics, such as ondansetron, should be administered to prevent these complications.

Wound Care and Infection Prevention

Meticulous wound care is essential to prevent infection. Incisions should be cleaned regularly with sterile saline and covered with appropriate dressings. Prophylactic antibiotics are typically administered to reduce the risk of surgical site infection. Signs of infection, such as redness, swelling, warmth, and purulent drainage, should be promptly addressed with appropriate antibiotic therapy and wound management.

The Rehabilitation Process: Restoring Function and Quality of Life

The rehabilitation phase aims to restore function, improve quality of life, and address any long-term sequelae of the injury. This requires a multifaceted approach involving dietary modifications, oral hygiene instructions, and physical therapy.

Dietary Modifications and Nutritional Support

Patients with Le Fort fractures often require dietary modifications to accommodate limitations in oral function. A liquid or soft diet is typically recommended in the initial post-operative period, gradually advancing to a more solid diet as tolerated. Adequate nutritional support is crucial for wound healing and overall recovery. Patients may require nutritional supplements to meet their caloric and protein needs.

Oral Hygiene Instructions

Maintaining meticulous oral hygiene is essential to prevent infection and promote healing. Patients should be instructed to brush their teeth gently with a soft-bristled toothbrush and rinse their mouth with an antiseptic mouthwash. Interdental cleaning with floss or interdental brushes should be avoided until the surgical sites have healed sufficiently.

Physical Therapy

Physical therapy can help restore range of motion, reduce swelling, and improve muscle strength. Patients may benefit from exercises to improve jaw opening, lateral movements, and protrusion. Scar massage can also help minimize scar tissue formation and improve skin mobility.

Potential Complications: Addressing Challenges and Promoting Resilience

Despite meticulous surgical technique and comprehensive post-operative care, complications can still occur. Awareness of these potential issues is crucial for early detection and prompt intervention.

Infection

Infection remains a significant concern following Le Fort fracture repair. Risk factors for infection include open fractures, contaminated wounds, and pre-existing medical conditions. Infections can range from superficial wound infections to deep-seated osteomyelitis. Treatment typically involves antibiotics, wound debridement, and removal of infected hardware.

Malocclusion

Malocclusion, or misalignment of the teeth, can result from inadequate fracture reduction, hardware failure, or scar contracture. Malocclusion can interfere with chewing, speech, and facial aesthetics. Treatment may involve orthodontic therapy, additional surgery, or a combination of both.

Non-union/Malunion

Non-union refers to the failure of a fracture to heal, while malunion refers to healing in an abnormal position. These complications can result from inadequate fracture fixation, infection, or poor patient compliance. Treatment typically involves revision surgery to achieve proper fracture alignment and promote bone healing. Bone grafting may be necessary to fill defects and stimulate bone formation.

CSF Leak

Cerebrospinal fluid (CSF) leak is a rare but serious complication that can occur with Le Fort III fractures or fractures involving the skull base. CSF leak can increase the risk of meningitis and other central nervous system infections. Treatment may involve conservative measures, such as bed rest and lumbar drainage, or surgical repair of the dural defect.

Diplopia

Diplopia, or double vision, can result from injury to the extraocular muscles or nerves, or from displacement of the orbital bones. Treatment may involve observation, prism glasses, or surgical correction of the orbital deformity.

Trismus

Trismus, or limited jaw opening, can result from muscle spasm, scar contracture, or temporomandibular joint dysfunction. Treatment may involve physical therapy, muscle relaxants, or surgical release of scar tissue.

Comprehensive Post-Operative Care: A Cornerstone of Successful Outcomes

In conclusion, comprehensive post-operative management is indispensable for achieving optimal outcomes following Le Fort fracture repair. Vigilant monitoring in the immediate post-operative period, followed by a structured rehabilitation program, can significantly reduce the risk of complications and improve the patient's quality of life. Early detection and prompt management of complications are crucial for preserving facial structure and function. A multidisciplinary approach, involving surgeons, nurses, physical therapists, and other healthcare professionals, is essential to provide the best possible care for these complex patients.

Special Considerations in Le Fort Fracture Management: Pediatric and Geriatric Patients

Following accurate diagnosis and classification, the focus shifts to treatment planning and surgical intervention. The overriding goal is to restore the patient's facial structure, achieving functional occlusion and an acceptable aesthetic outcome. This intricate reconstruction process demands a nuanced approach, especially when dealing with vulnerable populations like pediatric and geriatric patients. Their unique physiological characteristics necessitate modifications to standard surgical protocols and post-operative care regimens.

Pediatric Le Fort Fractures: A Landscape of Development

Managing Le Fort fractures in children presents a unique set of challenges related to their ongoing craniofacial development. Unlike adults, children possess developing teeth, active growth centers, and thinner bone structures. These anatomical and physiological differences significantly influence treatment strategies and expected outcomes.

Growth Center Sensitivity

The presence of growth centers in the midface mandates careful surgical planning to avoid iatrogenic injury, which could lead to growth disturbances and facial asymmetry. Aggressive periosteal stripping and rigid fixation across growth centers are generally avoided in favor of more conservative approaches.

Dental Development

Developing teeth within the line of fracture pose additional complications. Surgical manipulation must be meticulously planned to minimize damage to tooth buds and avoid future dental abnormalities. Consultation with a pediatric dentist is crucial in these cases.

Treatment Modalities in Children

Open reduction and internal fixation (ORIF) techniques may be adapted in pediatric cases. Bioresorbable plates and screws are frequently favored in pediatric surgery. They eliminate the need for a second surgery for hardware removal and allow for more physiological bone remodeling. Closed reduction and conservative management may also be considered in select minimally displaced fractures in very young patients.

Geriatric Le Fort Fractures: The Impact of Aging

Geriatric patients with Le Fort fractures present a different set of considerations, primarily related to age-related physiological changes and comorbidities. Osteoporosis, reduced bone density, and compromised healing capacity are common factors that influence treatment decisions and outcomes.

Bone Quality and Fixation

Osteoporotic bone poses challenges for stable fixation. Standard screws may not provide adequate purchase in weakened bone, increasing the risk of hardware failure and non-union. Techniques such as bicortical screw placement and bone grafting may be required to improve fixation stability. Augmentation with bone substitutes might also be considered to improve bony union.

Comorbidities and Systemic Health

The presence of age-related comorbidities, such as cardiovascular disease, diabetes, and respiratory issues, further complicates the management of geriatric patients with Le Fort fractures. Pre-operative medical optimization and close collaboration with other medical specialists are essential to minimize the risk of complications.

Prolonged Healing and Rehabilitation

Geriatric patients often experience slower healing rates and require more intensive rehabilitation programs. Careful attention must be paid to nutritional support, wound care, and prevention of complications such as pneumonia and deep vein thrombosis. Early mobilization and physical therapy are crucial for restoring function and preventing disability.

Association with Other Facial Trauma: A Holistic Perspective

Le Fort fractures rarely occur in isolation. They frequently accompany other forms of facial trauma, including nasal fractures, zygomaticomaxillary complex fractures, and orbital fractures. A comprehensive assessment is therefore crucial to identify all injuries and develop a holistic treatment plan. Failure to address associated injuries can lead to suboptimal outcomes and persistent functional or aesthetic deficits. The surgeon should approach each patient case by treating the whole complex and not simply targeting the single obvious Le Fort fracture.

Video: Le Fort Fracture: Causes, Symptoms & Treatment

Frequently Asked Questions About Le Fort Fractures

What kind of trauma typically causes a le fort fracture?

High-impact facial trauma is the primary cause. Common causes include motor vehicle accidents, significant falls, assaults involving blunt force, and sporting injuries. These fractures involve separation of all or a portion of the midface from the cranial base.

What are the main differences between the three types of le fort fractures?

Le Fort fractures are classified into three types based on the fracture line's location. Type I involves a horizontal fracture separating the palate. Type II involves a pyramidal fracture including the nasal bones and maxilla. Type III involves complete craniofacial disjunction, separating the entire midface from the skull.

Besides visible deformities, what are some other common symptoms?

Besides obvious facial distortion, other frequent symptoms include significant swelling, bruising around the eyes, nosebleeds, difficulty breathing or swallowing, numbness in the face or teeth, double vision, and cerebrospinal fluid (CSF) leakage from the nose. Pain is also a significant symptom associated with any le fort fracture.

How is a le fort fracture usually treated?

Treatment almost always involves surgery. Open reduction and internal fixation (ORIF) is the standard approach, using plates and screws to realign and stabilize the fractured bones. The goals are to restore facial structure and function, and prevent long-term complications. The success of treatment depends on the severity and type of le fort fracture.

Dealing with a Le Fort fracture can be a tough experience, but understanding the causes, recognizing the symptoms, and exploring the treatment options puts you in a much stronger position. Remember to always consult with a qualified medical professional for personalized advice and care if you suspect a Le Fort fracture.